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Predisposing factors for surgical complications in chronic prostatitis and fibrosis of the prostate
Artur Colța*†, Vitalii Ghicavîi†
https://doi.org/10.52645/MJHS.2022.4.05
Prostatitis is an inflammatory process of the prostate, which continues to be considered one of the most common urological diseases in men under 45. Predisposing factors such as trophic, microcirculatory, and congestive disorders contribute to the onset and development of the inflammatory process in the prostate, as do risk factors such as the urethral catheter, urethrocystoscopy, endoscopic surgery for infection, and deterioration of the integrity of the urethral epithelium. The purpose of this study was to determine the impact of chronic inflammation and fibrosis of the prostate on urodynamics and local prostatic microcirculation and to evaluate the efficacy of conservative treatment.
Clinical patterns and complete blood count parameters in young patients with primary myelofibrosis in the prefibrotic stage
Nina Sghibneva-Bobeico1,2*, Vasile Musteata1,2, Maria Robu1,2, Lidia Jalba1, Larisa Musteata2, Ala Dorogan1, Cristina Dudnic1, Elena Covalschi1
https://doi.org/10.52645/MJHS.2022.4.04
Primary myelofibrosis is a rare myeloproliferative neoplasm that affects 0.2-1.5 people per 100,000. As a rule, the diagnosis is confirmed after 60 years, but recently, hematologists around the world have encountered the problem of primary myelofibrosis in young people. The classic manifestations of myelofibrosis are characterized by splenomegaly, cytopenia, and bone marrow fibrosis, but in patients younger than 40 years, the diagnosis is most often made in the prefibrotic stage of the neoplasm. The aim of the paper is to identify and evaluate the clinical and hematological features of primary myelofibrosis in young patients in the prefibrotic stage.
Impact of comorbidities on the clinical and ultrasound features of psoriatic arthritis
Psoriatic arthritis (PsA) is a chronic musculoskeletal and cutaneous inflammatory disease that affects about 20-30% of patients with psoriasis. In addition to musculoskeletal and cutaneous manifestations, patients with PsA have a higher prevalence of comorbidities compared to the general population. More than half of patients with PsA have at least one comorbidity, with up to 40% of patients having more than three comorbidities. PsA has a particularly strong association with metabolic diseases and, as a result, with cardiovascular diseases (CVD).
Loco-regional analgesia in oncology. Influence on cancer recurrence rate. Literature review
Ruslan Baltaga1,2, Andrei Perciun3, Andrei Badan1, Radu Turchin1,4, Valeria Cotelea1,2*
https://doi.org/10.52645/MJHS.2023.1.12
A major role and, at the same time, a question mark, both for patients and doctors, is the possibility that drugs and anesthetic techniques influence cancer metastasis. Cancer is the leading cause of death worldwide. This trend will continue in the future. Most of the deaths of cancer patients are due to complications arising from metastases. The metastasis process of a tumor depends on its intrinsic properties and interaction with the host. The treatment of tumors by performing a surgical intervention, radical or palliative, has a significant impact. For these reasons, the rate of survival and migration of cancer cells in the perioperative period is studied quite insistently and complexly. Thus, surgical intervention and anesthetic support in cancer patients becomes of great importance, because it represents the vulnerable link, both from the point of view of the operation itself, as well as the possibility that drugs, anesthetic techniques may or may not influence tumor metastasis.
The current assessment and management of thyroid nodules
Cristina Cojocaru*, Alin Bour
https://doi.org/10.52645/MJHS.2023.1.11
The widespread use of diagnostic imaging favored the increasing incidence of thyroid nodules. Although most of nodules are benign, their clinical importance lies in the need to exclude malignancy. In assessing and managing thyroid nodules may occur the phenomenon of overdiagnosis and overtreatment on one hand and the risk of missing an aggressive thyroid cancer on the other hand. The equilibrium that has to be reached by health care providers.
Morality, ethics, and professional deontology: non-traditional sources of medico-pharmaceutical law
Moral, ethical, and professional deontological rules have a substantial impact on the social relations of legal regulation regarding liability for abuses and violations of citizens' rights – people taking medication – patients as part of the health care system. The identification of the place and role of moral norms, ethics, and professional deontology, their quality as specific non-traditional primary sources in the development of the health care system, and the sub-branch of pharmaceutical law in the Republic of Moldova were the focus of the present study.
Qualitative and quantitative determination of proteins in extracts of some medicinal plants
Angelica Ohindovschi1,3*, Margit Cichna-Markl2, Maria Cojocaru-Toma1,3, Tatiana Calalb3, Nicolae Ciobanu1,6, Cornelia Fursenco3,4, Cristina Ciobanu1,6, Anna Benea1,3, Livia Uncu4,5
https://doi.org/10.52645/MJHS.2023.1.09
Global consumption of plant protein is increasing and high-fiber plants have health benefits through valuable phytochemicals. Plant proteins serve as an alternative to animal proteins to meet consumer demand on the one hand and reduce the risk of disease on the other