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Recovery of patients with gout
Larisa Rotaru1,2†*, Liliana Groppa1,2†, Serghei Popa1†, Tamilla Nurseitova3†, Cornelia Cornea1†
https://doi.org/10.52645/MJHS.2022.3.10
The incidence and prevalence of gout have increased worldwide in recent decades. Scientists at the Rochester Epidemiology Project (MN, USA) have seen a two-fold increase in the incidence of primary gout (patients without diuretic exposure) over a 20-year period, which ended in 1996. The increase of incidence may be related due to the difficulty and often unsatisfactory treatment options. The aim of the study was to systematize the recommendations on dietary treatment, and medication for patients with gout.
Molecular and cellular biomarkers in status epilepticus and epilepsy
Cornelia Calcîi1,3*, Svetlana Hadjiu1,3, Iulia Calistru1, Andrei Calistru1, Ludmila Feghiu1,4, Olga Constantin1, Stanislav Groppa2,4
https://doi.org/10.52645/MJHS.2022.3.08
Peripheral biomarkers have numerous uses in the treatment, prognosis, and pharmacovigilance of epilepsy. Unfortunately, no peripheral biomarker has demonstrated proven efficacy, although several options are being investigated. In this article, we want to analyze the main areas in which peripheral biomarkers can present their usefulness, including participation in the processes of inflammation, dysfunction of the blood-brain barrier, changes in metabolism, hormones, and growth factors.
Risk assessment of pericoronitis in correlation with the position of the inferior third molar
The inferior third molar is the most encountered impacted permanent tooth. Pericoronitis of the lower third molar is a term used to describe the inflammation around the crown of a tooth, usually of an incompletely erupted mandibular third molar. Mandibular molar impactions are usually mesioangular, distoangular, vertical, and horizontal. The position and type of the impaction may affect the development of pericoronitis. This study was conducted to assess the positions of the lower wisdom tooth as a risk factor for pericoronitis.
Importance of urodynamic testing prior to treatment for overactive bladder in women
Mihaela Ivanov1*†, Emil Ceban1†
https://doi.org/10.52645/MJHS.2022.3.04
Overactive bladder (OAB) is a common and chronic complex of symptoms that increases in prevalence with advancing age and has a known adverse effect on the quality of life. OAB is a highly prevalent condition affecting 16.6% people from Europe. Women are more commonly affected, and there is an increased incidence with age. Studies in the United States suggest a prevalence of up to 43% in women. The use of urodynamics in the diagnosis of OAB remains controversial. Although it is a gold standard diagnostic test for detrusor overactivity, it is an invasive procedure and therefore should be limited to those with refractory OAB.
Features of lipid metabolism in membranes of rat cells at experimental traumatic brain injury on the background of chronic alcohol intoxication
Valentin Kresyun1†, Vladlena Godovan1†*, Elena Sokolik1†, Natalya Kresyun1†
https://doi.org/10.52645/MJHS.2022.3.03
Alcohol intoxication is often the cause of traumatic brain injury. The purpose of the work was to study the features of lipid metabolism in erythrocytes and mitochondria of the cerebral cortex cell membranes of rats in traumatic brain injury on the background of chronic alcohol intoxication.