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Refractive lens exchange in a patient with high myopia and myopic astigmatism: a clinical case report
Serghei Porada1,2*, Iulia Tanurcova1,2, Ala Paduca1,3
https://doi.org/10.52645/MJHS.2025.4.15
Refractive lens exchange is increasingly utilized for visual rehabilitation in patients with high myopia unsuitable for corneal refractive procedures. While effective, refractive lens exchange with intraocular lens implantation significantly improves visual acuity in young patients with high myopia and astigmatism, while maintaining a low risk of postoperative retinal complications, provided that thorough preoperative vitreoretinal assessment is conducted. However, it carries potential risks, notably retinal complications.
Digital planning in orthodontics. Applicability of the Kau, Pan, Gallerano index in contemporary orthodontics
Valentina Trifan*, Ana Bolgari, Iana Baiceva, Daniela Trifan, Irina Zumbreanu
https://doi.org/10.52645/MJHS.2025.4.14
Digital planning in modern orthodontics is crucial in contemporary era, as it allows dentists to expand the limits of patients’ diagnosis and clinical treatment. Using tools such as 3D scanners, cone beam computed tomography with various software gives clinicians the opportunity to achieve more precise diagnoses and accurate predictions of treatments. In this way, digital imaging offers a precise localization of impacted canines which allows for the integration and applications of the Kau, Pan, Gallerano index
β-adrenergic agonists and β-antagonists in sport performance: a narrative synthesis of pharmacological effects and anti-doping implications
Tatiana Chiriac1*, Ina Pogonea1, Tatiana Timercan2, Artiom Jucov 3,4, Silvia Stratulat2, Alisa Tăbîrță5, Victoria Chihai5
https://doi.org/10.52645/MJHS.2025.4.13
In the context of increasingly intense athletic competition, athletes are motivated to enhance their performance through various methods, including the use of pharmacological substances that act on the adrenergic system. Among these, β2-adrenergic agonists are employed for their metabolic effects and their role in increasing endurance, whereas β-adrenergic antagonists are used in precision sports to reduce tremor and control anxiety. Both classes of substances present potential benefits as well as health risks, and are subject to strict regulations in high-performance sports.
Stigmatization in medicine: impact on patients, healthcare providers, and ethical standards of care
nga Anisei-Cojocaru*, Liliana Rogozea
https://doi.org/10.52645/MJHS.2025.4.11
Stigmatization is a social phenomenon that adversely affects not only access to care but also the quality of medical services. In the medical context, stigma occurs when patients – or even healthcare professionals – are treated differently, with prejudice or a lack of empathy, due to certain traits, conditions, or social affiliations.
Current concepts in the management of bone lesions in multiple myeloma
Bone lesions remain a serious, unresolved issue in patients with multiple myeloma. The management of myeloma-related bone disease involves a multimodal approach, including chemotherapy, bone antiresorptive agents (bisphosphonates), radiotherapy, pharmacological pain management, minimally invasive percutaneous orthopedic procedures, and invasive surgical interventions.
Toxico-hygienic and economic aspects of acute non-occupational chemical poisonings in the Republic of Moldova during the period 2019-2023
Tatiana Tonu1*, Iurie Pînzaru2, Ludmila Goma3, Natalia Daniliuc4
https://doi.org/10.52645/MJHS.2025.4.09
Acute non-occupational chemical poisoning is a current public health problem in the Republic of Moldova, affecting both children and adults. The global increase in the use of chemical substances and mixtures raises the risk of chemical poisoning, which ranks fourth among the causes of injury in children, after road traffic injuries, burns, and drowning. It also generates a significant economic burden, and its quantification contributes to making informed decisions regarding the efficient allocation of resources.
A simple method for preparing herbal reference standards based on salting-out solvent extraction
Igor Casian*, Ana Casian
https://doi.org/10.52645/MJHS.2025.4.08
The expansion of the range of herbal medicinal products requires the availability of a large number of different reference standards for their analysis. A possible solution is the use of herbal reference standards (HRS), which, in turn, requires the development of simple production methods that meet all the requirements for reference standards
The relationship between zinc levels and immunological biomarkers in oral fluid in children affected by dental caries
Svetlana Plamadeală1*, Olga Tagadiuc2, Aurelia Spinei1
https://doi.org/10.52645/MJHS.2025.4.07
Dental caries is one of the most widespread diseases in the human population, and the causes of increased susceptibility to dental caries remain of continuing interest to researchers. Active immunological components of oral fluid significantly influence the evolution of dental caries. The aim of this research is to study the relationship between zinc levels, the antimicrobial peptide LL-37, and transforming growth factor beta-1 in oral fluid, and the incidence of dental caries in children.
Prevalence and severity of depression, anxiety, and cognitive impairment in acute ischemic stroke patients: a cross-sectional study
Mihaela Belous1*, Radislav Cosulean1, Dorin Jelaga1,2, Igor Nastas1,2, Jana Chihai1,2, Madalina Bivol1, Larisa Boronin1,2, Andrei Esanu2, Alina Bologan2, Cornelia Adeola2
https://doi.org/10.52645/MJHS.2025.4.06
Post-stroke depression (PSD) and anxiety are common neuropsychiatric sequelae of stroke, occurring in roughly one-third of survivors. Cognitive impairment is also frequently observed, affecting up to half of stroke patients. These conditions adversely impact rehabilitation and quality of life. This study aimed to determine the prevalence and severity of depression, anxiety, and cognitive deficits in patients with acute ischemic stroke.
Descriptive analysis of pediatric laryngeal papillomatosis in Republic of Moldova: epidemiological and clinical characteristics
Daniela Cernev*, Vasile Cabac
https://doi.org/10.52645/MJHS.2025.4.05
Recurrent laryngeal papillomatosis is a rare but significant pediatric condition caused by human papillomavirus types 6 and 11. Characterized by the repeated growth of benign exophytic lesions in the respiratory tract, recurrent laryngeal papillomatosis poses a considerable burden due to its recurrent nature, frequent need for surgical intervention, and potential impact on respiratory function. This study aims to describe the epidemiological profile of pediatric recurrent laryngeal papillomatosis in the Republic of Moldova, identify high-risk groups, and explore the socioeconomic implications of the disease.