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The Tirone David procedure in acute type A aortic dissection – when, how, and why? The experience of Professor Dr. George I.M. Georgescu Institute of Cardiovascular Diseases
Grigore Tinică1,2,3, Mihail Enache1,2, Andrei Țărus1,2, Silviu Stoleriu1,2, Alberto Bacușcă1,2
https://doi.org/10.52645/MJHS.2025.3.01
Acute type A aortic dissection represents a life-threatening cardiovascular emergency with catastrophic natural history and extremely high mortality in the absence of prompt surgical intervention. Over the last decades, surgical management has evolved from supracoronary replacement and composite root replacement (Bentall procedure) towards valve-sparing strategies, among which the Tirone David reimplantation procedure has gained increasing acceptance.
Assessment of osteoarticular morbidity in regions with different boron concentrations in deep drinking water of the Republic of Moldova
Maria-Victoria Racu*1, Iurie Pînzaru1, Elena Ciobanu2, Lucia Mazur-Nicorici3
https://doi.org/10.52645/MJHS.2025.2.07
Even if boron is not yet recognized as an essential element for the human body, its insufficient intake is considered harmful, especially for the osteoarticular system. A daily intake of at least 3 mg of boron can fortify bone mass and prevent the onset of osteoarthritis, rheumatoid arthritis, and osteoporosis. This research aims to assess the morbidity caused by rheumatoid arthritis and inflammatory polyarthropathies in the population from regions with different boron concentrations in deep drinking water of the Republic of Moldova.
Interdental contact – morphofunctional component of the stomatognathic system
Victoria Ababii*, Diana Marcu, Sergiu Ciobanu
https://doi.org/10.52645/MJHS.2025.2.05
As part of the interproximal assembly, the interdental contact is a morphofunctional component that contributes to the stabilization of teeth, maintaining the integrity of the dental arch, protecting the papilla, and preventing food impaction. The aim of the study is to radiologically evaluate the proximal morphology of restored surfaces on lateral teeth and the positioning of the interdental contact
Exploring knowledge and perceptions of domestic violence among medical students and physicians in the Republic of Moldova
Petru Glavan*, Andrei Pădure, Anatolii Bondarev
https://doi.org/10.52645/MJHS.2025.2.04
Domestic violence is one of the most widespread human rights violations in the world. The health sector plays a vital role in preventing domestic violence, helping to identify abuse early, providing victims with the necessary treatment, and referring them to appropriate care. The paper aims to explore the level of knowledge and perceptions in the field of domestic violence among current and future physicians in the Republic of Moldova, in order to assess their educational needs
Development of a mathematical model for thrombosis risk prediction using serum biomarkers
Dan Croitoru1, Iurie Trohin1, Ecaterina Pavlovschi2, Oleg Arnaut3, Eugen Cerevan4
https://doi.org/10.52645/MJHS.2025.2.03
Thrombosis is a frequently underdiagnosed condition associated with high mortality in neglected cases. Many factors, including geoheliophysical and biochemical ones, are responsible for thrombosis modulation. Routine investigations may sometimes be inconsistent and, thus, unreliable in a clinical setting.
Thrombosis and hemostatic abnormalities in non-Hodgkin lymphoma
Sanda Buruiana1*, Minodora Mazur2
https://doi.org/10.52645/MJHS.2025.2.02
Non-Hodgkin lymphoma is a heterogeneous group of malignant lymphoid tumors. Hemostasis disorders in non-Hodgkin lymphoma are often asymptomatic but can develop into severe complications. The risk of venous thromboembolism increases according to the totality of risk factors assessed directly in each individual patient, based on age, gender, comorbidities, performance status, and both congenital and acquired thrombophilia
Congenital disorders of glycosylation - diagnosis experience in the Republic of Moldova
Daniela Blăniță1*, Chiril Boiciuc1, Alina Nicolescu2, Victoria Sacara3, Natalia Ușurelu1
https://doi.org/10.52645/MJHS.2025.2.01
Congenital disorders of glycosylation (CDG) represent a group of rare diseases with multisystem involvement and exponential expansion, characterized by defects in the glycosylation process, which is essential for the proper functioning of proteins and lipids. These often manifest under the guise of other pathologies. The objective of the study was to diagnose CDG using Isoelectric Focusing of Transferrin (IEFT) in the Republic of Moldova and to identify diseases that mimic CDG.
The dosage and biological role of carotenoids and chlorophylls in species of the genus Galium L.
Angelica Ohindovschi1,2*, Tatiana Calalb1, Maria Cojocaru-Toma1,2
https://doi.org/10.52645/MJHS.2025.1.08
Carotenoids and chlorophylls are plant pigments that play a vital role in plant life, participating in the process of photosynthesis and in the synthesis of growth regulators, stress signalers and fungicide attack agents. Research from the last decades has shown that, widely used as nutrients, chlorophyll and carotenoid pigments have beneficial effects on the human body. They exert antioxidant, energizing, detoxifying, anti-inflammatory properties, and can be applied in the prevention and treatment of 21st century diseases (cancer, cardiovascular diseases, low immunity), which are related to numerous causal factors (excessive chemicalization of the food industry, progressive climate change and environmental pollution), which reflects on the quality of human health.
Testing and validation of the questionnaire for evaluating the chemical composition of bottled water in relation to public health
Maria Curteanu1,2*, Valentina Marinescu3, Alina Ferdohleb4, Ion Bahnarel1, Iurie Pînzaru1,2, Elena Ciobanu1
https://doi.org/10.52645/MJHS.2025.1.07
In the context of increasing global consumption of bottled water, assessing its chemical composition and impact on public health becomes essential. Although perceived as a safe alternative, bottled water exhibits variability in its chemical composition, and advanced filtration methods can remove essential minerals. Consumers opt for bottled water due to its taste and convenience, yet awareness of associated risks remains limited. This study proposes the development and validation of a questionnaire to evaluate public perceptions of bottled water